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A review : Peptic Ulcer Disease Hello guys, well, here I am again, alone, as syapi has gone back to BTW, the relapsing peptic ulcer keeps assailing me nowadays in spite of my so-organized food managing scheme (breakfast, lunch and dinner on time) and last night, I've got this heartburn sensation over my epigastria region. Upon self-examination, the pointing sign which is a characteristic of PUD, is positive (pointing sign appears to be positive when one can precisely point at the site of the pain, not a diffuse one though) meaning that PUD has once again succeeded in overwhelming my confidence and dignity as well as the frame of my mind. I ran out of the house and bought myself FAMODAR (famotidine) which selectively block the H2 receptor ( resulting in diminished acid secretion from the parietal cells) and to my relief, the symptoms and the pain ceased down after like one hour or so. Do correct me if I am wrong on the infos below. PUD is actually a discontinuity of the mucosal epithelium lining the stomach or duodenum and Helicobacter Pylori remains as the major basis, found in nearly 80 percent of all PUD sufferers. Stress, NSAID abuse, smoking and etcetera may precipitate one's problem. We have got here 2 types of medical treatment or the what-so-called the step-up treatment and the step down one. In the step-up method, you start with the weakest drugs followed by a stronger one and vice versa, meaning that if I use the step-down therapy, I will begin with Proton Pump Inhibitor (blocking the K/H pump) and then followed by H2 Blocker, antacids etc. If left untreated, I must say that the ulcer may lead to certain complications: 1) bleeding - one may encounter melena, which is black faeces resulting from the digested blood on the upper GIT 2) perforation - your ulcer may go deep enough to create a small hole 3) gastric outlet obstruction resulting from the fibrosed scars The complications may lead to death~~ BTW the triple eradication therapy is the golden rule, if one wishes to have the H.Pylori forever exterminated. It is a combination of three drugs, the Proton Pump Inhibitor, Metronidazole and Tetracycline. Well, I have purchased those three drugs from a pharmacy for like 2 years ago but unfortunately I keep postponing the therapy hence they reached the expiry date without me noticing em muahaha. bottomline : Prevention is always better than cure, so, take care of yourselves guys~~ p/s: Awe of Irbid has moved on to blogspot. Click on this link to be teleported right to his blog. Welcome to the world of blogging~~ | baez-kun at 10:33 PM
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